In an earnings estimate, the South Korean tech giant predicted an operating profit of SKW 6.1 trillion (roughly Rs. 33,997 crores) for the October-December period, up from SKW 5.4 trillion a year earlier.
The figure was below the estimate of SKW 6.64 trillion, given by analysts surveyed by Bloomberg News, and also marked a 7.5 percent drop from the previous quarter.
Samsung lost more than $8 billion (roughly Rs. 53,329 crores) in market value in 2015, with its flagship smartphone business sandwiched by top-end rivals like Apple's iPhone and lower-end devices from fast-growing Chinese outfits like Huawei and Xiaomi.
The company's shares posted a third straight annual decline last year, dropping 5.1 percent.
Sales were expected to be SKW 53 trillion in the fourth quarter, the company said, again slightly below analyst estimates.
Friday's forecast, which comes ahead of audited results to be released later this month, did not provide a net income figure or breakdown of divisional earnings.
Losses in Samsung's mobile division have partially been mitigated by brisk business in chips and displays.
That is because as well as providing the chips for the company's own handsets, Samsung's semiconductor unit also makes the processors for a number of other companies including Apple.
"The profit from semiconductors and display panels offset the weak performances in smartphones and consumer electronics in 2015," said Greg Noh, analyst at HMC Investment Securities.
"But we are expecting a drop in the momentum for demand in all finished goods in 2016, and that will lead to a decrease in earnings in the parts sector," Noh told AFP.
After peaking at SKW 10.1 trillion in the third quarter of 2013, Samsung's operating profit hit a bottom of SKW 4.6 trillion in the corresponding period of 2014 before climbing back up gradually.
As Samsung's reliance on the chipmaking business grew, the firm in May began building a new $14.3 billion (roughly Rs. 95,326 crores) chip plant in Pyeongtaek, 65 kilometres (40 miles) south of Seoul.
This investment in the factory, which is to begin production in 2017, is the largest the firm has ever committed to a single plant.
Last month, Samsung replaced the head of its mobile business and promoted the chairman's daughter in an effort to reassert its smartphone dominance amid a generational power transfer in the founding Lee family.
Samsung Group chairman Lee Kun-Hee has remained bedridden since suffering a stroke in 2014.
The Lee family controls the vast conglomerate through a complex web of share cross-holdings in group subsidiaries.
Samsung's share price rose in early trade by as much as 1.1 percent after the announcement before falling back slightly.